Nursing 321

NURS 321: Pathophysiology

Prerequisites: BIOL 322

Credit Hours: (3)

Major pathophysiologic concepts are explored. Theories relating etiology, pathogenesis, and clinical manifestations are used to study common disease processes. Concepts from anatomy and physiology provide the foundation for exploring human dysfunction. Concepts learned in this course are basic to the health professions. This course is open to all students.


Detailed Description of Content of the Course

The objectives and content of this Pre-Nursing Course are derived from the School of Nursing’s philosophy and conceptual framework, and facilitate achievement of the School’s program objectives. Additionally, the major topics and skills covered in this course represent areas covered on standardized achievement examinations and the NCLEX-RN Test Plan. Current research and advancement in theory and clinical practice also determine content.

1. Cellular Physiology
2. Cellular Dysfunction
3. Neoplasia
4. Immune Physiology
5. Immune Dysfunction
6. Alterations in Hematological Function
7. Alterations in Cardiovascular function
8. Alterations in Respiratory Function
9. Fluids and Electrolytes
10. Acid-Base Imbalances
11. Alterations in Renal Function
12. Alterations in Gastrointestinal Function
13. Alterations in Reproductive Function
14. Alterations in Neurological Function
15. Alterations in Musculoskeletal and Connective Tissue Function


Detailed Description of Conduct of Course

The following strategies will be employed: lecture, discussion, multimedia, case studies, and small group work.


Goals and Objectives of the Course

Upon successful completion of the course, the student will be able to:

  • Discuss the etiologies, pathogenesis, clinical manifestations, and treatment implications of common disorders of human dysfunction.
  • Critically analyze clinical data to identify logical connections, sort important and unimportant data, and identify potential pathophysiologic processes.
  • Predict usual clinical manifestations and appropriate treatments for clients with defined medical diagnoses.
  • Predict the consequences of particular interventions based on logical theories of pathogenesis.


Assessment Measures

May include:

  • Exams; Quizzes
  • Paper
  • Project, Individual or Group
  • Care Plan
  • Oral Presentations
  • Class Participation

The course grade is determined by an evaluation of the extent to which the student meets the stated course objectives. Students must have a minimum of 80% (“C”) in theory, measured through testing. Other written work will be included in the final grade after the minimum 80% (“C”) has been attained through testing.


Other Course Information

Course may be appropriate for students in disciplines other than Nursing.

Honor Code: By accepting admission to Radford University, each student makes a commitment to understand, support, and abide by the University Honor Code without compromise or exception. Violations of academic integrity will not be tolerated. This class will be conducted in strict observance of the Honor Code. Refer to your Student Handbook for details.

Students with Disabilities: If you are seeking classroom accommodations under the Americans With Disabilities Act, you are required to register with the Center for Accessibility Services (CAS). The CAS is located in Suites 301-327, Russell Hall. Call the CAS at 540-831-6350. To receive academic accommodations for this class, please obtain the proper CAS forms and meet with the instructor no later than the second week of the semester.

Attendance: For Attendance policies and other course-related requirements, see School of Nursing Undergraduate Student Handbook and Course Description.


Review and Approval
April 2006 Undergraduate Curriculum Marcella Griggs, Director