Chemistry 461

CHEM 461

Catalog Entry

CHEM 461. Advanced Organic Chemistry
Three hours lecture (3).

Prerequisite: CHEM 302

Study of advanced topics in organic chemistry.


Detailed Description of the Content of the Course

This course is for students with a strong interest in organic chemistry; particularly those students planning careers and/or graduate programs that require a knowledge of the subject. An outline of topics covered is: The exact content of the course may vary from year to year depending on student interest, but the following topics are usually included:

1. Review of the principles of stereoisomerism including isomer numbers, optical activity, specification of configuration, stereoselective and stereospecific reactions, enantiotopic and diastereotropic ligands and faces.
2. Use of the principles of stereochemistry in the study of reaction mechanisms in organic chemistry and biochemistry including biological oxidation-reduction reactions and nucleophilic substitution reactions.
3. Molecular orbitals: wave equations, aromatic character, orbital symmetry effects or concerted reactions.


Detailed Description of Conduct of the Course

The course uses a lecture format with the student encouraged to ask questions and discuss the material being covered. Outside reading and homework are required.


Goals and Objectives of the Course

To help students prepare for graduate study and/or careers requiring a knowledge of organic chemistry. The material presented is required for advanced study in organic chemistry and biochemistry, but often omitted from a first year organic chemistry course due to time limitation. Thus 461 is of benefit to those students entering graduate programs or going directly into jobs involving research in organic chemistry or biochemistry.


Assessment Measures

The students earn grades dependent on their test scores and the quality of their homework. Two tests and a final examination are given.


Other Course Information



Review and Approval

September 2001 Reviewed by Walter S. Jaronski, Chair