Nutrition and Dietetics 414

NUTR 414: Advanced Nutrition & Biochemistry I

Prerequisites: NUTR 304, NUTR 316, NUTR 317, CHEM 103, CHEM 101 or CHEM 120, BIOL 322, BIOL 334, and senior standing

Credit Hours: (4)

Presents a detailed study of the nutrients and their role in human intermediary metabolism and physiology.


Detailed Description of Content of Course

The purpose of this course is to present the biochemical, metabolic and physiological principles and their interrelationships to normal nutrition; designed for upper division nutrition students; update on current scientific discoveries and/or concepts related to human nutrition. Major area of nutrition which will be covered include:

  • Cellular physiology and its role in nutrition
  • Gastrointestinal physiology and its role in cellular nourishment
  • Enzyme kinetics and bioenergetics
  • Study the digestion absorption, transport and metabolic utilization of the energy-yielding nutrients, protein, carbohydrates and lipids
  • The biochemical roles in energy production and metabolic pathways for these nutrients are reviewed with emphasis on reaction that have relevance to health. Energy transformation and interrelationships among the nutrients are included.
  • The digestion, absorption, transport, and metabolism of regulatory nutrients which include water-soluble and fat-soluble vitamins, macro and micro minerals are examined. In addition, fiber will be reviewed for its regulatory role in metabolism.
  • Homeostatic maintenance of body fluids and electrolyte balance, body composition, energy balance and weight control will be studied. Other systems include the circulatory, digestive and endocrine will be recognized for their role in human metabolism.
  • Interpretation of nutrition information, critical evaluation of research and how to design a research proposal will be considered.


Detailed Description of Conduct of Course

This course will include lecture, problem sets for practical application, case studies, self-directed study, oral and written research proposal, and writing-to-learn activities. The course is designed to provide students with an in-depth knowledge in nutrition metabolism which helps meet their entry level registered dietitian core curriculum requirements.


Goals and Objectives of the Course

Successful completion of this course will enable the student to:

  • Apply critical thinking to interpret and evaluate current nutrition research.
  • Demonstrate technical writing and oral presentation skills.
  • Understand how macronutrients are metabolized to energy or biologically related products in the body.
  • Identify the biochemical and physiologic functions of proteins, lipids, carbohydrates, vitamins and minerals.
  • Discuss the fundamental structure and catalysis of amino acids an peptides, proteins, enzymes, lipids, biological membranes, carbohydrates, and nucleotides and nucleic acids.
  • Describe the principles of bioenergetics and nutrient metabolism.
  • Understand the integration and hormonal regulation of nutrients, vitamins, and minerals in intermediate metabolism.
  • Discuss carbohydrates, lipids, and nitrogen-containing compounds from the standpoint of individuals organ systems indicating processes of digestion, absorption, transport, and homeostasis of body fluids, electrolytes, and essential nutrients.
  • Understand how measurements used in assessment of nutrient status reflect nutrient reserves.
  • Demonstrate ability to apply knowledge of nutrition, biochemistry, and physiology in the analysis of clinical case studies.
  • Understand the rationale for the level of intakes established by the Dietary Reference Intakes (DRI) for each nutrient; know the DRI for each nutrient.


Assessment Measures

Evaluation of the student will be determined from graded written examinations (problem based questions), graded problem sets, graded oral and written research proposal, and participation in class discussions and activities.


Other Course Information

This course, in part, fulfills the requirements for the Didactic Program in Dietetics approved by the American Dietetic Association.


Review and Approval

December 2002 Updated Anne Alexander, Chair

Revised 3/6/09