Biology 405

BIOL 405
Histology

1. Catalog Entry

BIOL 405
Histology

Credit hours (4) Three hours lecture; three hours laboratory
Prerequisite: A grade of "C" or better in BIOL 105 or BIOL 132 and at least 4 hours of anatomy and/or physiology courses (BIOL 310, 311, 322, 351, 410, 411)
    
An introduction to components, arrangements and adaptations of vertebrate animal tissues. Taught from a comparative perspective, but with special emphasis on mammalian tissues and mammalian organ systems.

2. Detailed Description of Course

    1) Lecture
        a. Introduction
            i.   Microscopy
            ii.  Overview of Cell Components and the Cell Cycle
            iii. Overview of Vertebrate Anatomy and Development
        b. Primary Tissue Types
            i.   Epithelia
            ii.  Connective Tissues
            iii. Muscle
            iv.  Nervous Tissue
        c. Histology of the Organ Systems
            i.   Cardiovascular System
            ii.  Lymphatic System
            iii. Integumentary System
            iv.  Digestive System
            v.   Respiratory System
            vi.  Urinary System
            vii. Endocrine System
            viii.Male and Female Reproductive Systems
            ix.  Central Nervous System
            x.   Special Sensory Organs
    2) Laboratory
        a. Analysis of prepared slides using the compound light microscope
            i.   Study of basic cell structure and epithelial types
            ii.  Study of connective tissues
            iii. Study of muscle and nervous tissues
            iv.  Study of the integument
            v.   Study of the cardiovascular and lymphatic systems
            vi.  Study of the digestive system
            vii. Study of the respiratory system and the urinary system
            viii.Study of the male and female reproductive systems
            ix.  Study of the endocrine system
        b. Histotechnology
            i.   Introduction to micro-techniques and project design
            ii.  Tissue fixation, dehydration and embedding
            iii. Sectioning tissues and preparing slides
            iv.  Staining
            v.   Examination and analysis of tissues using compound light microscopy

3. Detailed Description of Conduct of Course

The lecture portion of the course may be conducted using a variety of techniques and aids in addition to the traditional lecture format. A variety of visual aids including images of slides, videos, and computer-generated graphics may be used to enhance the lectures. Class discussion will be encouraged. The laboratory experience will consist of two parts. The microscopy portion of the lab will be devoted to the examination and analysis of prepared samples using compound light microscopy. The histotechnology portion of the lab may be devoted to short, independent research projects. Students will learn techniques necessary for preparing tissue samples for light microscopy, and will then analyze slides they make to answer basic research questions.  
 
4. Goals and Objectives of the Course

Having successfully completed this course the student will be able to:
    1) Use the compound light microscope to identify the primary mammalian tissue types, as well as the histology of the
        mammalian organ systems.
    2) Discuss the relationships between structure and function of tissues examined.
    3) Make predictions about function based on structure even when they have not previously seen the tissue.
    4) Describe how tissues are prepared for light microscopy
    5) Use these methods to prepare at least one tissue type for investigation
    6) Use histological techniques to answer scientific questions in anatomy

5. Assessment Measures

Each student will be tested on his or her knowledge of histology through a variety of tests and quizzes that may include illustrated essays, matching and multiple response questions, and identification of structures in microscopic sections and whole mounts. Each student may be required to write a research report for an independent lab project, and will be assessed on the ability to design and carry out his or her research. Students may also be evaluated on their contributions to discussions.

6. Other Course Information

None

Review and Approval

March 18, 2005

2012

June 20, 2015